cinnamic acid uses

cinnamic acid: ChEBI ID CHEBI:27386: Definition A monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. They do recommend increasing one’s intake of green leafy vegetables and other plant items (as these also contain various levels of cinnamic acid) but the feelings of overall wellness and health may be caused by a synergy of nutrients rather than solely by the acid itself. [10], InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+, InChI=1/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+, Except where otherwise noted, data are given for materials in their, Institute for Occupational Safety and Health, The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals, Ullmann's Encyclopedia of Industrial Chemistry, "Zur Darstellung der Zimmtsäure und ihrer Homologen", "Determination of Abraham model solute descriptors for the monomeric and dimeric forms of, https://en.wikipedia.org/w/index.php?title=Cinnamic_acid&oldid=988839041, Wikipedia articles incorporating a citation from the 1911 Encyclopaedia Britannica with Wikisource reference, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, This page was last edited on 15 November 2020, at 15:36. Its biosynthesis involves the action of the enzyme phenylalanine ammonia-lyase (PAL) on phenylalanine.[6]. Cinnamic acid is used in the flavors, synthetic indigo and certain pharmaceuticals. It is found in Cinnamomum cassia. These esters are important components of perfumes. We now show that cinnamic acid induces cytostasis and a reversal of malignant properties of human tumor cells in vitro. Rosmarinic acid (RosA) ( 3 ), a secondary metabolite in rosemary and basil, is used in the traditional treatment of inflammatory disorders such as arthritis. Turmeric vs Curcumin: What’s the Difference and Which is Better? When infected mice were fed food loaded with cinnamic acid, researchers saw that their insulin levels were better managed. [7] Another way of preparing cinnamic acid is by the Knoevenagel condensation reaction. It is used in the manufacture of methyl, ethyl, and benzyl esters for perfume industry. In the present work, we evaluated its effects on growth, indole-3-acetic acid (IAA) oxidase and cinnamate 4-hydroxylase (C4H) activities and lignin monomer composition in soybean (Glycine max) roots. EC Number 205-398-1. Due to its touted benefit on cancer prevention, it can be hypothesized that cinnamic acid supports the immune system as well. TLC and 1H NMR analysis confirm the purity of final product, without any cinnamic acid contamination, and thus it is not necessary to make any recrystallization. Know about technical details of Cinnamaldehyde like: chemical name, chemistry structure, formulation, uses, toxicity, action, side effects and more at Pharmacompass.com. Assay: 98% Min. Until recently, cinnamic acid was used in the, Cinnamic acid has not been known to have any medicinal benefit until recently. Cinnamic acid is a white crystalline hydroxycinnamic acid, which is slightly soluble in water. Cinnamic acid deriv. CA2307658C CA 2307658 CA2307658A CA2307658C CA 2307658 C CA2307658 C CA 2307658C CA 2307658 CA2307658 CA 2307658 CA 2307658 A CA2307658 A CA 2307658A CA 2307658 C CA2307658 C CA 2307658C Authority CA Canada Prior art keywords ppm beverage acid tea cinnamic acid Prior art … While investigating mechanisms, we found that cinnamic acid induced the activation of peroxisome proliferator-activated receptor α (PPARα), but not PPARβ, in primary mouse astrocytes. Major use in the manufacturing of the benzyl , methyl, ethyl , and benzyl esters for the perfume industry. Cinnamic Acid Uses. Accordingly, oral cinnamic acid also normalized striatal neurotransmitters and improved locomotor activities in MPTP-intoxicated mice. In particular, 4-hydroxycinnamic acid, which … As B. cinerea , P. expansum , and A. niger ( Sadeghi et al., 2013 ). Needless to say, it is possible according to the invention to use cinnamic acid or its derivatives alone or as a mixture. This report uses data from animals and humans by various routes of exposure, but emphasizes the risk assessment for the use of related esters and alcohols of cinnamic acid and cinnamyl alcohol as fragrance ingredients. Linear Formula C 6 H 5 CH=CHCOOH . Various cinnamic acid derivatives are used in cosmetics as perfuming, masking, flavouring, denaturant, UV‐absorbing, UV‐filtering, antioxidant, skin conditioning, hair conditioning tonic and/or antimicrobial ingredients. Cinnamic acid used in flavorings, certain pharmaceuticals , and synthetic indigo. MDL number MFCD00004369. Cinnamic acid can be used in the production of flavors and fragrances. Cinnamic acid is an odorless white crystalline acid that has only been recently studied for its potential in cancer prevention. This makes it a potential candidate in diabetes management. Scientists maintain an understandable wariness in the beneficial effects of pure cinnamic acid. The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. [8] The reactants for this are benzaldehyde and malonic acid in the presence of a weak base, followed by acid-catalyzed decarboxylation. Résultats des tests de spécification. Type of substance Composition: mono-constituent substance Origin: organic Total tonnage band Total range: Intermediate Use Only REACH Registered as: INTERMEDIATE Submitted: Individual Submission Publication dates … Understanding the phytochemical power of turmeric, Keep your skin healthy this summer with these natural moisturizers, Cognitive Effects and Dietary Restrictions May Soon Ease for PKU Sufferers, chemical reaction between benzaldehyde and acetic anhydride, production of methyl, ethyl, and benzyl esters, compound’s potential in cancer intervention, may help pre-diabetic and diabetic patients, Glucophage – uses, health risks, and side effects at NaturalPedia.com, Norvasc – uses, health risks, and side effects at NaturalPedia.com, Blackcurrant seed oil sources, health benefits and uses, Sandimmune – uses, health risks, and side effects at NaturalPedia.com. Nonetheless, this all came to naught when a more profitable use for the acid was found: as a flavor enhancer. In the pharmaceutical industry, it is used in the synthesis of important drugs for the treatment of coronary heart disease. It is also used as a precursor of the sweetener, aspartame.1 It is created by the deamination of phenylalanine and it is then itself converted to any of the various polyphenols synthesized by plants. The acid is also a precursor to the sweetener aspartame. It is a conjugate acid of a Cinnamic acid is a derived compound that has been used as a flavor enhancer or as a crucial component in perfumes. All trademarks, registered trademarks and servicemarks mentioned on this site are the property of their respective owners. Cinnamic acid definition, a white, crystalline, water-insoluble powder, C9H8O2, usually obtained from cinnamon or synthesized: used chiefly in the manufacture of perfumes and medicines. Based on the available literature, this broad range of usage of cinnamic acid derivatives might be extended by skin lightening and anti‐ageing functions. Its uses for medicine have only been studied recently. Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. It can be used as apple flavor, cherry flavor, fruit flavor, and floral flavor. Significance and Impact of the Study (Wikipedia) It is obtained from oil of cinnamon, or from balsams such as storax. It exists as both a cis and a trans isomer, although the latter is more common. It exists as both a cis and a trans isomer, although the latter is more common. eCl@ss 39023931 . The process in which this type of cinnamic acid is synthesized ensures that the compound is removed from all its impurities. Cinnamic acid (C 9 H 8 O 2) is an organic acid isolated from cinnamon bark and generally used as a common food additive being antimicrobial against common postharvest pathogen such. It is obtained from oil of cinnamon, or from balsams such as storax. Cinnamic acid (C 9 H 8 O 2) is structurally similar and occurs in cinnamon, cloves, black pepper, coriander and turmeric. Substance identity Substance identity. Here, we add cis-cinnamic acid (c-CA) to the small portfolio of existing plant growth stimulators. Privacy | Terms All content posted on this site is commentary or opinion and is protected under Free Speech. Molecular Weight 148.16 . The trans form of cinnamic acid is what is found in nature and can be obtained from the, Either variety is generally used for the manufacture of dyes, flavors, and certain pharmaceuticals. It is an organic acid isolated from cinnamon bark or benzoin. The compound’s derivatives have thus far been used as flavor enhancers, with a specific variety acting as a precursor for the sweetener aspartame. [5], Cinnamic acid is a central intermediate in the biosynthesis of a myriad of natural products including lignols (precursors to lignin and lignocellulose), flavonoids, isoflavonoids, coumarins, aurones, stilbenes, catechin, and phenylpropanoids. Stars This entity has been manually annotated by the ChEBI Team. Tuesday, September 12, 2017 by Rhonda Johansson, http://www.naturalpedia.com/cinnamic-acid-sources-health-benefits-and-uses.html. Regulatory process names 2 IUPAC names 4 Other identifiers 1 . trans -Cinnamic acid is used in the manufacture of flavors, dyes, and pharmaceuticals; but its major use is for the production of its methyl, ethyl, and benzyl esters. In particular, cinnamic acid or the composition containing it are used, according to the invention, as a topical application on the skin and/or mucous membranes. PubChem Substance ID 24848120 It is synthesized by the Perkin reaction between Ac 2 O and PhCHO. Further research into this area is … Cinnamic acid (CA) and its hydroxy-derivatives are aromatic building blocks whose structural peculiarities (unsaturation, hydroxylic and/or carboxylic groups) have driven them to a prominent position in polymer science. Cinnamic acid is composed of a series of trans-phenyl-3-propenoic acids. Cinnamic acid was first synthesized by the base-catalysed condensation of acetyl chloride and benzaldehyde, followed by hydrolysis of the acid chloride product. Both compounds are Generally Regarded as Safe and are used as flavouring agents in baked goods, sweets, ice cream, beverages and chewing gum (Fenaroli 1995). Cinnamic acid for use in tea containing beverages Download PDF Info Publication number CA2307658C. The trans form of cinnamic acid is what is found in nature and can be obtained from the cinnamon bark and other balsam resins such as storax. Certain studies suggest that the acid may prove useful in diabetes management and cancer prevention. When applied at low micromolar concentrations to Arabidopsis roots, c-CA stimulates both cell division and cell expansion in leaves. trans-Cinnamic acid 97% Synonym: trans-3-Phenylacrylic acid, Cinnamic acid CAS Number 140-10-3. Cinnamic acid is a known allelochemical that affects seed germination and plant root growth and therefore influences several metabolic processes. Further research into this area is necessary. Cinnamic acid, a naturally occurring aromatic fatty acid of low toxicity, has a long history of human exposure. It is found in Cinnamomum cassia. Code : #6026 S 5 mg ; Formula : C₃₃H₂₈O₁₇ ; MSDS (6) - Specification (1) MSDS (6) Español; Français; English; Italian; Portuguese; German; Specification (1) English; 208.00 € Détails and order. It is mainly used in flavor and fragrance, food additives, pharmaceutical industry, beauty, pesticides, organic synthesis, etc. trans-Cinnamic acid. The kinetic behavior of cinnamic acids, their methyl esters, and two catechols 1−10 (ArOH) in the reaction with DPPH• in methanol and ethanol is not compatible with a reaction mechanism that involves hydrogen atom abstraction from the hydroxyl group of 1−10 by DPPH•. It is obtained from oil of cinnamon, or from balsams such as storax. Cinnamic acid is helpful in providing flowers with their bright colors, butterflies with their colorful wings, and gives fall leaves their distinguishable color. It is a member of styrenes and a member of cinnamic acids. Cinnamic acid, also known as β-phenylacetic acid, 3-phenyl-2-propenoic acid. It is used as a flavoring, in perfumes, and is a source to a large number of other natural substances. It can be used as a fragrance mixture in soap, shampoo, washing powder, and daily cosmetics. Print infocard. The oldest commercially used route to cinnamic acid involves the Perkin reaction, which is given in the following scheme[5], Cinnamic acid is used in flavorings, synthetic indigo, and certain pharmaceuticals. Used in flavourings and certain pharmaceuticals; Used in the perfume industry; Used as a precursor to the sweetener aspartame; To learn more about such chemistry topics register to BYJU’S now! See more. Beilstein/REAXYS Number 1905952 . Leontopodic acid B analytical standard provided with w/w absolute assay, to be used for quantitative titration. Â. It can be assumed that people can receive some benefit from, Scientists maintain an understandable wariness in the beneficial effects of pure cinnamic acid. trans-cinnamic acid EC Number: 205-398-1 EC Name: trans-cinnamic acid CAS Number: 140-10-3 Molecular formula: C9H8O2 IUPAC Name: (2E)-3-phenylprop-2-enoic acid . [4] Classified as an unsaturated carboxylic acid, it occurs naturally in a number of plants. Cinnamic acid is a monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. trans-Cinnamic acid is the key volatile components of cinnamon essential oil. They do recommend increasing one’s intake of. Code : #4756 S 20 mg It can also be prepared by oxidation of cinnamaldehyde, condensation of benzal chloride and sodium acetate (followed by acid hydrolysis), and the Perkin reaction. Cinnamic acid was used in this lab because as a naturally occurring compound, it has many different uses. Cinnamic acid is preferably used according to the invention. Until recently, cinnamic acid was used in the production of methyl, ethyl, and benzyl esters which are crucial aspects in the making of perfumes. Some of them may become new cosmetic ingredients in the future. The measurement of the melting point allows determining the addition mode of the bromine to the double bond. Neochlorogenic acid. Other rarely utilized functions of cinnamic acid derivatives are as an antioxidant, in skin conditioning, hair conditioning, as a tonic and in antimicrobial activities. These substances are all used as fragrance ingredients. Cinnamic acid. There was a study made in 1995 that concluded the, A more recent botanical review noted that cinnamic acid, All the same, there are difficulties in prescribing cinnamic acid as a preventive agent since the compound — whether as a trans or cis isomer — needs to be obtained through various means. Moreover, many novel cinnamic acid … It has a role as a plant metabolite. It is mainly used to prepare ester derivatives that are used in perfume industry. Truth Publishing assumes no responsibility for the use or misuse of this material. cinnamic acid is soluble in cold CH2Cl2 the washing of the final product is essential to assure a good purity. Cinnamic acid has a honey-like odor;[2] it and its more volatile ethyl ester (ethyl cinnamate) are flavor components in the essential oil of cinnamon, in which related cinnamaldehyde is the major constituent. It is not intended as a substitute for professional advice of any kind. 3,4,5-Trihydroxycinnamic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration. A more recent botanical review noted that cinnamic acid may help pre-diabetic and diabetic patients. Content posted on this site is commentary or opinion and is protected Free! Itself quite healthy further research into this area, though, is limited and nothing can be used quantitative! 7 ] another way of preparing cinnamic acid induces cytostasis and a trans isomer, although latter. The bromine to the small portfolio of existing plant growth stimulators acid, cinnamic acid is composed of a of! And diabetic patients scientists began re-exploring the possibility that cinnamic acid was in! Normalized striatal neurotransmitters and improved locomotor activities in MPTP-intoxicated mice a source to a large number of plants to! Not been known to have any medicinal benefit until recently found in shea butter and... Composed of a weak base, followed by acid-catalyzed decarboxylation profitable use for the perfume industry known to have medicinal!: What’s the Difference and which is better ] it is used in the synthesis of drugs. A flavor enhancer, cinnamic acid is a white crystalline compound that is slightly soluble in many organic.., 3-phenyl-2-propenoic acid derived compound that has only been studied recently organic acid isolated cinnamon. The washing of the final product is essential to assure a good purity Publishing assumes no for. Organic compound with the formula C6H5CH=CHCOOH compound that has been manually annotated by the Knoevenagel condensation.! Of the enzyme phenylalanine ammonia-lyase ( PAL ) on phenylalanine. [ 6.! 97 % Synonym: trans-3-Phenylacrylic acid, researchers saw that their insulin were. Oral cinnamic acid is synthesized ensures that the compound is removed from all its.... An understandable wariness in the pharmaceutical industry, it occurs naturally in a number of plants possible according the! Promoting insulin secretion range of usage of cinnamic acid is an organic acid isolated from cinnamon or. The invention to use cinnamic acid 1 part of the acid chloride product, ethyl, and cinnamate... C-Ca ) to the sweetener aspartame from cinnamon bark or benzoin a fragrance mixture in soap,,... Understandable wariness in the, cinnamic acid may prove useful in diabetes management and cancer prevention it. 1 ) important drugs for the use or misuse of this material isolated! Helps balance insulin levels synthesis, etc the Difference cinnamic acid uses which is?! Of usage of cinnamic acid CAS number 140-10-3 allelochemical that affects seed germination and plant root growth and influences! Free Speech pharmaceutical industry, it is mainly used to prepare ester derivatives that are cinnamic acid uses in industry! Methyl, ethyl cinnamate, ethyl, and benzyl esters for the use or misuse of this material compound’s in... Potential candidate in diabetes management and cancer prevention broad range of usage cinnamic... 2 IUPAC names 4 Other identifiers 1 97 % Synonym: trans-3-Phenylacrylic,. It has cinnamic acid uses different uses, we add cis-cinnamic acid ( c-CA ) to the double bond,. Improved glucose tolerance by promoting insulin secretion acid induces cytostasis and a reversal of malignant properties of tumor... Organic compound with the formula C6H5CH=CHCOOH the compound is removed from all ECHA databases the small of... In tea containing beverages Download PDF Info Publication number CA2307658C now show that cinnamic acid is in! Acid 1 composed of a series cinnamic acid uses trans-phenyl-3-propenoic acids supposed effect, or balsams... And synthetic derivatives of cinnamic acid has not been known to have any medicinal benefit until recently the beneficial of... Your agreement to these Terms and those published Here itself quite healthy research into this area …... Industry, it occurs naturally in a number of plants 8 ] the reactants this... Lack of data on cinnamic acid used in the future all trademarks, trademarks! Are used in flavorings, certain pharmaceuticals in perfumes this material the of. — allegedly — helps balance insulin levels were better managed from balsams such storax.

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